Conditions PROSE Treats

Post-Transplant Dry Eye and Poor Vision

"Miracle workers! Every morning I experience going from functional blindness to perfect vision when I put in my prosthetic devices."  — Post-transplant patient

82% of patients with problems — including dry eye, poor vision and/or severe astigmatism — after corneal transplant (PK, PKP) reported significant success with BostonSight® PROSE and 96% reported moderate or significant success.

Contact us today to find out if we can help you!

Download PROSE: Information for Patients and Doctors here

What problems can develop from a corneal transplant?

A cornea transplant involves replacing a diseased or scarred cornea with a new one; about 40,000 cornea transplants are performed each year, many of them for individuals with keratoconus.

Issues that can develop from corneal transplants include dry eyes, poor vision and astigmatism. More severe complications include rejection of the new cornea which must be treated immediately by your ophthalmologist.

How BostonSight PROSE Treatment Can Help

Hundreds of patients with dry eye, eye pain, light sensitivity and poor vision post-corneal transplant - just like you - have had their vision restored and quality of life transformed with our innovative treatment: prosthetic replacement of the ocular surface ecosystem (PROSE). PROSE uses FDA-approved custom made prosthetic devices to replace or support impaired ocular surface system functions that protect and enable vision.

Device schematic - white

The prosthetic devices created during PROSE are transparent domes, about the size of a nickel. They look similar to an oversized hard contact lens and resemble a margarita glass without the stem in shape. PROSE devices fit under the eyelids, vaulting the damaged cornea and resting on the sclera (the relatively insensitive white tissue of the eye). Worn during waking hours, patients are trained in daily application, removal and cleaning as part of the treatment process.

PROSE devices are made out of a highly gas-permeable hard plastic that allows oxygen to reach the cornea. They are designed to create a space between the prosthetic device and the eye that is filled with sterile saline. The liquid remains in the reservoir, providing constant lubrication by bathing the eye in a pool of artificial tears.

Benefits of BostonSight PROSE

  • Reduces symptoms of dry eye and light sensitivity and supports healing by restoring a healthy ocular surface environment
  • Improves blurry vision by masking irregularities / astigmatism on the cornea’s surface and transmitting a sharp image to the back of the eye
  • Prevents further damage by protecting and shielding the cornea against the environment and eyelids

Note: The prosthetic devices used in BostonSight PROSE treatment were formerly known as Boston Ocular Surface Prosthesis (BOS-P), Boston Scleral Lens devices and Boston Scleral Lens Prosthetic Devices. 

Updated 1/14

Back to the Skies

Over the years Donna had tried all of the treatment options available to her... unfortunately, eventually her sight deteriorated to the point where she was legally blind...read more.

Symptoms and Treatment Success

A 2010 BFS survey of 39 people with post-transplant dry eye and/or poor vision (26 PROSE patients) found that:

  • 95% had difficulty with work or hobbies that require seeing up close
  • 92% had difficulty reading regular print newspapers, magazines or websites
  • 84% had difficulty driving at night
  • 75% had moderate or severe light sensitivity
  • 73% had moderate or severe eye pain

When asked about their success with various treatments:

  • 3% with artificial tears, lubricant gels or ointments
  • 12% with rigid gas-permeable (RGP) contact lenses
  • 20% with topical antibiotics
  • 22% with topical steroids

82% had significant success with BostonSight® PROSE treatment*

96% had moderate or significant success with BostonSight PROSE

* Survey questions refer to success with Boston Ocular Surface Prosthesis (BOS-P) and Boston Scleral Lenses used exculsively in BostonSight PROSE treatment.

Read more patient survey results in our Report Back to the Community.